Table 2 Results of the SGA analyses for all query strains crossed to the single-gene deletion collection

Query strain	No. negative genetic interactions	No. positive genetic interactions	Total
hrq1Δ	76	41	117
hrq1-K318A	84	48	132
sgs1Δ	164	148	312
sgs1-K706A	189	172	361
hrq1Δ sgs1Δ	361	333	694
hrq1Δ sgs1-K706A	392	396	788
hrq1-K318A sgs1Δ	442	438	880
hrq1-K318A sgs1-K706A	400	396	796