Table 2 Genes significantly de-repressed in Sce.IR wing discs
SymbolNameRatioaFDRMolecular functionBiological rolesGO-terms (biological function)
Abd-BAbdominal-B0.439166671.67E-19Hox transcription factorBithorax complex Hox gene controlling posterior abdominal segments; external genitalia and gonads, and post-mating-responseepithelium development, anatomical structure morphogenesis
ococelliless0.170266672.66E-07Paired-like homeobox transcription factorregulator of rhodopsin expression and axonal targeting in the retinaepithelium development, anatomical structure morphogenesis
abd-Aabdominal-A0.115433333.91E-07Hox transcription factorbithorax complex Hox gene controlling identity of embryonic segmentsepithelium development, anatomical structure morphogenesis
mirrmirror0.17558.49E-06iroquois homeobox transcription factordorso-ventral axis; eye formation; embryonic segmentation; PNS developmentepithelium development, anatomical structure morphogenesis
nubnubbin0.085733331.61E-05POU/homeodomain transcription factorwing formation; midgut stem cell proliferation and enterocyte differentiationanatomical structure morphogenesis
cadcaudal0.176133334.41E-05Hox-like homeobox transcription factoranterior/posterior patterning, organ morphogenesis innate immune systemepithelium development, anatomical structure morphogenesis
Inx2Innexin 20.213166670.00027954gap junction proteinepithelial organization and polarity of epidermis, regulation of organ size and stem cell behaviorepithelium development, anatomical structure morphogenesis
CAH2Carbonic anhydrase 20.356133330.00038658Carbonic anhydraseCatalyze the CO2 hydration reaction
tuptailup0.065266670.0015028LIM homeobox transcription factorneuronal sub-type identity, including motor, serotonergic and dopaminergic neuron identity. It regulates germ band retraction, dorsal closure, muscle and heart developmentepithelium development, anatomical structure morphogenesis
Sp1Sp10.046833330.00190136Sp-family of Cys2His2-type zinc finger transcription factorsventral thoracic appendage specification; leg growth; type-II neuroblast developmentepithelium development, anatomical structure morphogenesis
PdkPdk0.138766670.00347056Pyruvate dehydrogenase kinasePyruvate dehydrogenase kinase
Robo2Roundabout-20.110066670.00481979Robo-family cell surface receptorAxon guidance receptorepithelium development, anatomical structure morphogenesis
CG3777CG37770.089133330.00529072unknownunknown
pimpimples0.50680.00719975SecurinInhibits Separaseepithelium development, anatomical structure morphogenesis
CG3262CG32620.391933330.00728925unknown; interpro domain [Flagellum site-determining protein YlxH/ Fe-S cluster assembling factor NBP35]unknown
PscPosterior sex combs0.093333330.00911746Component of PRC1 complexPcG epigenetic repressionAnatomical structure morphogenesis .
CG34293CG34293-RA0.613266670.00994297Unknown; Interpro domain [Small subunit of serine palmitoyltransferase-like]CG34293-RA
  • a Values are for transcript isoform with highest ratio - see Supplementary Data File 1.