Table 4 Genes whose deletion cause the strongest growth phenotypes when combined with the hrq1 and sgs1 mutants
Query strainNegative interactionsaPositive interactions
hrq1ΔSPO16, RAD14, YSC83, MRM2, SLX9, YUR1, YDR455C, MUP3, PHO5SHE1
hrq1-K318AHAP3, TCO89, VPS41, HAP2, RAD14, CBC2, TOM70VAM7, SHE1, MRM2, EAP1, ARP8
sgs1ΔYBR099C, PBY1, YBR100W, RRM3, SLX4, MMS4, SRS2, SLX9, WSS1, SLX1, SWC5MKS1, EAP1, YLR235C, HXT2, RPS10A, AIM14, EOS1, RTG1, BUD31, OCA5, YJL206C-A, RPL20B, RTG2, GRR1, RTG3, YGL214W, UGA1, YNL046W, MIR1, HAP2, LDH1
sgs1-K706ASRS2, SLX4, SLX9, SLX1, SWC5, RNH203, WSS1, SPO16, SLX8, ASK10, RNH202, MUS81, YBR099C, PBY1, YBR100W, MMS4, YSC83, HAP3, ELG1EMC5, RPL20B, ITC1, RIM101, BUD31, SSP1, RAD54, YGL214W, SHU1
hrq1Δ sgs1ΔMUS81, MMS4, PBY1, YBR100W, YBR099C, CAT2, SLX1, WSS1, SLX4, SRS2, AEP2, SAE2, RRM3, BUL1, CAT8, YMR031W-A, ICY1, RPL6B, DSK2, SLX8, RIT1, SWI4, COX7, RGM1, ASK10, TRM732, ROY1, YMR265CMUB1, SNZ1, YMR102C, UBP1, MFG1, HBT1, EOS1, MIR1, AIP1, PTP1, BRE4, GCS1, RPO41, SSB1, MRM2, OST4, HAP2, KCH1
hrq1Δ sgs1-K706ASLX1, MUS81, SRS2, RRM3, BUL1, SLX8, AEP2, ASK10, YMR031W-A, SLX4, ELG1, WSS1, YSC83, TRM732, SAE2, ROY1, YMR194C-A, YBR099C, OCA5, SWI4YMR075C-A, IRC21, EOS1, CSM2, YKR040C, SAM1, SNZ1, RIM9, RPO41, HBT1, RPL20B, YMR102C, SEG1, MFG1, AIP1, HAP3, STV1, OST4, BUD31, KCH1, BRE4, YMR087W, PTP1, GCS1, TKL1, YJR120W, SSB1, WWM1
hrq1-K318A sgs1ΔMUS81, SRS2, WSS1, SLX4, RTT107, SLX1, CAT2, ASK10, YMR194C-A, PBY1, TRM732, RRM3, CAT8, YBR099C, MMS4, YBR100W, RIT1, BUL1, ICY1, RAD27UBP1, RRI1, WHI4, UBX4, GYP7, YMR075C-A, ENV10, MUB1, SNZ1, HBT1, MIR1, EOS1, YMR087W, SNO1, FMP45, SEG1, RPS10A, IMP2, YDR161W, SRT1, MFG1, BUD31, RPL20B, YLR346C, SHU1, YMR102C, MBR1, SPO16, RPO41, AIP1, PTP1, GCS1, YDR514C, SCY1, BRE4, SSB1, OST4
hrq1-K318A sgs1-K706AMUS81, YJR084W, SLX1, RRM3, CAT2, SWI4, WSS1, YBR100W, SLX8, YBR099C, INP1, YMR194C-A, SLX4, TRM732, FPR2, YDR186C, YMR245W, MMS4, PBY1, KAP114, SRS2, OCA5SNZ1, YDL211C, EOS1, APJ1, IGO1, SRT1, MBR1, MFG1, YJR120W, YLR235C, RIM9, IRC21, BUD31, HBT1, YDR008C, CSM2, RRI1, BRE4, YMR087W, YMR102C, RPO41, GCS1, PTP1, SSB1, HAP3
  • a Negative interactors are listed from largest absolute value of their SGA score to the smallest, but positive interactors are listed from the smallest absolute value of their SGA score to the largest.