Table 2 SVM-generated classifiers (Asthma Gene Expression signatures) for sample types (blood, Macrophage, induced sputum) that are widely used to study the pathology of asthma. Percent predictive accuracy for each classifier has also been indicated
Tissue TypeAsthma Gene Signature (for >80% predictive accuracy)% correct prediction
Blood (GSE69683)MYD88, MYL12A, BOLA2, HBXIP, ACSL1, VPS24, GPM6B, F5, PDE7A, AB11FIP3, ZNF785, TCF4, RAB11A, GPR109B, GNAQ, DIS3L2,, SLC7A5P1/P2, TSR2, AMICA1, CR1, QRICH1, SERBP1, ZNF37A, DERL2, ZBTB20, CDC42SE1, NSMAF, KIAA0562, NT5C2, DAPP1, ATP6V0E1, LOC203274, TMEM59, NAPEPLD, ANXA3, WIPI2, ATAD5, LARS, PTBP1, SPG7, DNAJC16, IL6ST, CLN8, SAT1, EVI2B, MRPS5, AQP9, RPP14, ZNF747, GAPT83
Macrophage Cells (GSE2125)KBTBD2, UPF3A, MLLT10, PSPC1, ST3GAL1, ARFRP1, TRIM14, EIF4G1, BM25, CDK11A/B,83
Induced Sputum (GSE76262)IL18R1, TLR7, GPR85, LIMA1, SPINT1, EIF1AY, PDCD6, MGAT4A, CSTA, LOC10012984596