| KLF6 (Kruppel like factor 6) | 5 | AirEpi, Macrophages, FibroDistal, CD8+, Nasal | Yes |
| BCL10 (B-cell lymphoma/ leukemia 10) | 4 | Macrophages, FibroDistal, CD4+, Blood | Yes |
| HOXB13 Homeobox protein Hox-B13 | 4 | Macrophages, Sputum, FibroDistal, Nasal | No |
| IFNB1(Interferon beta 1) | 4 | Sputum, FibroDistal, CD8+, Blood | Yes |
| Entinostat | 4 | Macrophages, FibroDistal, CD8, Nasal | No |
| ATOX1(Antioxidant 1 Copper Chaperone) | 3 | FibroDistal, CD4, FibroProximal | No |
| BAMBI(BMP and activin membrane bound inhibitor) | 3 | Macrophages, Sputum, Blood | Yes |
| BMS-345541 | 3 | FibroDistal, CD8+, Nasal | Yes |
| CCNL1 (cyclin L1) | 3 | Macrophages, FibroDistal, CD8+ | No |
| CDCA8 (cell division cycle associated 8) | 3 | AirEpi, CD8+, Blood | No |
| DHX8 (DEAH-box helicase 8) | 3 | Sputum, Bronchial, Blood | Yes |
| DTX2 (deltex E3 ubiquitin ligase) | 3 | AirEpi, Sputum, Nasal | No |
| KLF3 (Kruppel like factor 3) | 3 | Bronchial, FibroDistal, CD8+ | Yes |
| LASP1 (LIM and SH3 protein 1) | 3 | AirEpi, Macrophages, CD8+ | Yes |
| LOXL1 (lysyl oxidase like 1) | 3 | AirEpi, Sputum, Blood | Yes |
| PPP2R3C (protein phosphatase 2 regulatory subunit B’’gamma) | 3 | AirEpi, Macrophages, Blood | Yes |
| PREB(prolactin regulatory element binding) | 3 | Macrophages, FibroDistal, FibroProximal | No |
| PUF60 (poly-U binding splicing factor 60) | 3 | Macrophages, CD8+, Nasal | No |
| SORBS3 (sorbin and SH3 domain containing 3) | 3 | Macrophages, FibroProximal, Nasal | No |
| TRIP10 (Thyroid Hormone Receptor Interactor 10) | 3 | Macrophages, Bronchial, FibroDistal | No |
| XPO7 (Exportin 7) | 3 | AirEpi, Sputum, Bronchial | Yes |
| YWHAZ | 3 | AirEpi, Bronchial, Nasal | No |
| Calyculin | 3 | Macrophages, FibroDistal, Blood | No |