Table 3 Candidate Gene Summary
GroupEnsembl IDGeneDistance from SNPa (bp)Immune PathwaysDisease Associations
LG3ENSGACG00000014756f337,324Coagulation Cascade
LG3ENSGACG00000015273map2k2b84,711MAPK/ERK
LG3ENSGACG00000015282tcf3a58,000MAPK/ERK
LG3ENSGACG00000015301unc13a15,909ALS
LG3ENSGACG00000015386epha4b25,437MAPK/ERK
LG3ENSGACG00000015719cldn1810,244Tight Junctions
LG3ENSGACG00000016028ripk26,127NFkB
LG3ENSGACG00000016066tblxr1b16,774Autism
LG3ENSGACG00000016121rgs11,892Celiac Disease
LG3ENSGACG00000016159pik3R363,634MAPK/ERK
LG3ENSGACG00000016189scp2a0Wheat Allergy
LG3ENSGACG00000016212angptl35,349MAPK/ERK
LG3ENSGACG00000016323c8b972Complement Cascade
LG3ENSGACG00000016338c8a0Complement Cascade
LG8ENSGACG00000012681pias4a68,402NFkB
LG8ENSGACG00000012686map2k2a58,202MAPK/ERK
LG8ENSGACG00000012737tcf3b5,424MAPK/ERK
LG8ENSGACG00000013097borcs819.084MAPK/ERK
LG8ENSGACG00000013123ncan0MAPK/ERK
LG8ENSGACG00000013599camk46,656MAPK/ERK
LG8ENSGACG00000013618gadd45bb5,900MAPK/ERK; NFkB
LG8ENSGACG00000013753gabrb321,271Autism
LG8ENSGACG00000013771gabrg30Autism
LG8ENSGACG00000014026cldn3417,633Tight Junctions
LG8ENSGACG00000014029zgc:15331115,831Tight Junctions
LG8ENSGACG00000014071nek180,789ALS
LG8ENSGACG00000014199sgcb0Muscular Dystrophy
  • a indicates closest SNP LOD > 3.