Table 2 Single-copy genes in the MIG genomes are less likely to have orthologs with knockdown phenotypes in C. elegans
SpeciesDuplicated/Triplicated genesaSingle-copy genesbPc
Lethal knockdowndNon-lethal knockdowneLethal knockdowndNon-lethal knockdowne
Meloidogyne arenaria9061351771830.001
Meloidogyne incognita9141366691680.001
Meloidogyne javanica83312311503030.005
  • a Genes from M. hapla with C. elegans orthologs that have an RNA interference phenotype and 2 or 3 surviving homologs from the triploidy in the respective MIG genome.

  • b Genes from M. hapla with C. elegans orthologs that have an RNA interference phenotype with only 1 surviving homolog from the triploidy in the respective MIG genome.

  • c P-value of the hypothesis test of equal proportions of lethal knockdown phenotypes in C. elegans for the genes with 2 or 3 surviving paralogs and 1 surviving gene: Chi-square test with 1 degree of freedom.

  • d M. hapla genes where the corresponding ortholog in C. elegans is lethal when knocked down.

  • e M. hapla genes where the corresponding ortholog in C. elegans is not lethal when knocked down.