Table 3 Most frequently-occurring GO terms among enhancers with evidence of recent positive selection by nSL across tissues in Europeans
BP GO Terms# of tissuesMF GO Terms# of tissuesCC GO Terms# of tissues
Interferon gamma-mediated signaling pathway18MHC class II receptor activity18Integral component of luminal side of endoplasmic reticulum membrane19
Antigen processing and presentation of exogenous peptide antigen17MHC class II protein complex binding18ER to Golgi transport vesicle membrane18
T cell co-stimulation17Peptide antigen binding15trans-Golgi network membrane18
T cell receptor signaling pathway14TAP1 binding14Endosome membrane17
MHC class II protein complex assembly13Lysosomal membrane15
Endocytic vesicle membrane12
TAP complex12
MHC protein complex12