Table 2 Most frequently-occurring GO terms among enhancers with evidence of recent positive selection by nSL across tissues in Africans
BP GO Terms# of tissuesMF Go Terms# of tissuesCC GO Terms# of tissues
Antigen processing and presentation of exogenous peptide antigen18MHC class II receptor activity18trans-Golgi network membrane18
T cell co-stimulation18MHC class II protein complex binding18Integral component of luminal side of endoplasmic reticulum membrane18
Interferon-gamma-mediated signaling pathway17Peptide antigen binding15Endosome membrane18
T cell receptor signaling pathway16TAP1 binding13ER to Golgi transport vesicle membrane17
Antigen processing and presentation of exogenous peptide antigen via MHC class I TAP dependent15Peptide antigen-transporting ATPase activity12Lysosomal membrane16
MHC class II protein complex assembly14TAP2-binding10TAP complex14
MHC protein complex11