Table 4 The tetrad detection software applied to various simulated test sets using multiple different parameter settings
paramnoisemisscen callingsimD4 p-valueSeg 2:2Seg 2:1Run timeAcc.
small_defaultSmall (100 tetrads/1000 markers)Half (500 markers)00yes0.20.050.90.956.1100%
small_500_0000yes0.210.050.90.956.0100%
small_default00.05yes0.20.050.90.955.8100%
small_500_m0500.05yes0.190.050.90.955.7100%
small_default00.1yes0.20.050.90.956.2100%
small_500_m1000.1yes0.190.050.90.956.2100%
small_default_n050.050yes0.20.050.750.886.7100%
small_500_050.050yes0.210.050.750.886.7100%
small_default_n100.10yes0.20.050.60.8319.0100%
small_500_100.10yes0.240.050.60.838.1100%
small_defaultFull (984 markers)00yes0.20.050.90.9513.6100%
small_984_00_a00yes0.130.050.90.9512.9100%
small_984_00_b00yes0.180.050.90.9513.3100%
small_default00.05yes0.20.050.90.9513.3100%
small_984_m05_a00.05yes0.140.050.90.9512.3100%
small_984_m05_b00.05yes0.170.050.90.9512.8100%
small_default00.1yes0.20.050.90.9513.5100%
small_984_m10_a00.1yes0.130.050.90.9512.1100%
small_984_m10_b00.1yes0.180.050.90.9513.1100%
small_default_n050.050yes0.20.050.750.8814.3100%
small_984_050.050yes0.20.050.750.8814.4100%
small_default_n100.10yes0.20.050.60.8318.0100%
small_984_100.10yes0.220.050.60.8316.0100%
medium_defaultMedium (1000 tetrads/10000 markers)10% set (1000 markers)00no0.110.050.90.9502:11.1100%
medium_1000_0000no0.120.050.90.9502:10.2100%
medium_default00.05no0.110.050.90.9502:37.4100%
medium_1000_m0500.05no0.120.050.90.9502:48.3100%
medium_default00.1no0.110.050.90.9502:54.9100%
medium_1000_m1000.1no0.120.050.90.9502:27.2100%
medium_default_n050.050no0.110.050.750.8802:15:16.7100%
medium_1000_05_a0.050no0.140.050.750.8827:15.2100%
medium_1000_05_b0.050no0.160.050.750.8835:54.9100%
medium_default_n100.10no0.150.050.60.8320:06:24.199.8%
medium_1000_10_a0.10no0.150.080.60.8319:21:00.799.8%
medium_1000_10_b0.10no0.160.080.60.8314:14:47.799.8%
medium_1000_10_c0.10no0.170.080.60.8310:54:27.699.0%
medium_defaultFull (9984 markers)00no0.110.050.90.9503:39.1100%
medium_9984_00_a00no0.10.050.90.9503:38.2100%
medium_9984_00_b00no0.120.050.90.9503:42.0100%
medium_default00.05no0.110.050.90.9504:12.3100%
medium_9984_m05_a00.05no0.10.050.90.9504:09.1100%
medium_9984_m05_b00.05no0.120.050.90.9504:13.2100%
medium_default00.1no0.110.050.90.9503:38.2100%
medium_9984_m10_a00.1no0.090.050.90.9503:32.5100%
medium_9984_m10_b00.1no0.120.050.90.9503:36.2100%
medium_default_n050.050no0.110.050.750.8833:42.0100%
medium_9984_05_a0.050no0.120.050.750.8817:35.0100%
medium_9984_05_b0.050no0.130.050.750.8841:01.2100%
medium_default_n100.10no0.150.050.60.8350:53:33.1100%
medium_9984_10_a0.10no0.160.050.60.8339:08:46.5100%
medium_9984_10_b0.10no0.170.050.60.8326:43:15.6100%
large_defaultLarge (1000 tetrads/100000 markers)10% set (10000 markers)00no0.120.050.90.9503:36.6100%
large_10K_0000no0.070.050.90.9503:28.3100%
large_default00.05no0.120.050.90.9503:40.0100%
large_10K_m0500.05no0.110.050.90.9503:42.3100%
large_default00.1no0.120.050.90.9503:45.0100%
large_10K_m1000.1no0.090.050.90.9503:35.7100%
large_default_n050.50no0.120.050.750.8818:46.4100%
large_10K_05_a0.50no0.130.050.750.8844:50.8100%
large_default_n100.10no0.140.050.60.8348:06:51.2100%
large_10K_10_a0.10no0.160.050.60.8331:13:42.7100%
large_defaultHalf (50000 markers)00no0.120.050.90.9510:51.9100%
large_50K_00_a00no0.070.050.90.9510:45.2100%
large_default00.05no0.120.050.90.9510:41.2100%
large_50K_m05_a00.05no0.050.050.90.9508:33.1100%
large_default00.1no0.120.050.90.9510:43.9100%
large_50K_m10_a00.1no0.070.050.90.9510:40.6100%
large_default_n050.50no0.120.050.750.8836:59.5100%
large_50K_05_a0.50no0.140.050.750.8803:34:11.0100%
large_default_n100.10no0.140.050.60.83296:17:18.6100%
large_50K_10_a0.10no0.150.050.60.83198:09:45.4100%
large_50K_10_b0.10no0.170.050.60.8393:53:41.7100%