Table 1 Differences in gene editing efficiency of Mrjp1 or Pax6 at the different injection sites
BatchTarget geneInjection siteTotalSurvival1 (%)Mutated (%)Biallelic knockout
Non-mosaic (%)Mosaic (%)
m1Mrjp1Dorsal posterior side2617 (65.4%)2 (11.8%)00
m2Mrjp1Ventral cephalic side2415 (62.5%)14 (93.3%)5 (33.3%)6 (40.0%)
p3Pax6Ventral cephalic side2213 (59.1%)13 (100.0%)3 (23.1%)7 (53.8%)
  • 1 , the number of injected embryos that have developed into stage 9.