Table 3 Effects of pept-1 RNAi treatment on vulval induction level of different mutants of the EGF-Ras-MAPK signaling cascade. Statistical tests (One-Way-ANOVAs) were performed for each mutant separately testing for the effect of treatment (control vs. pept-1 RNAi) on the number of vulval cells induced (* P < 0.05, ** P < 0.01, *** P < 0.001, ns: non-significant)
GenotypeTreatmentInduced cells (Mean ± SE)N
lin-3(e1417)Control0.46 ± 0.1360
pept-1 RNAi1.16 ± 0.09 ***60
lin-3(n378)Control0.27 ± 0.0560
pept-1 RNAi2.26 ± 0.17 ***60
lin-3(mf75)Control0.00 ± 0.0045
pept-1 RNAi0.00 ± 0.00 ns44
let-23(sy1)Control0.12 ± 0.0848
pept-1 RNAi1.36 ± 0.17 ***60
let-23(sy1); lin-3(n378)Control0.00 ± 0.0045
pept-1 RNAi0.09 ± 0.06 ns60
sem-5(n2019)Control0.81 ± 0.1548
pept-1 RNAi1.60 ± 0.12 ***55
mpk-1(ku1)Control2.69 ± 0.0545
pept-1 RNAi2.99 ± 0.01 *45