Table 4 Effect sizes for the most highly associated GWAS SNPs and for the AGGAGAGAAG haplotype at the most highly associated regional heritability region. Models were run for each sex separately and included a pedigree relatedness as a random effect. Count and ID Count indicate the number of ACC measures and the number of unique individuals for each genotype, respectively. Wald.P indicates the P-value for a Wald test of genotype as a fixed effect
LocusSexGenotypeCountID CountSolutionS.E.Z RatioWald.P
cela1_red_10_26005249FemaleA/A (Intercept)982829.5750.73240.433.43e-06
A/G388114−3.2690.733−4.46
G/G377116−3.8880.786−4.944
MaleA/A (Intercept)27624.4050.96425.3278.90e-03
A/G24840−1.8130.993−1.826
G/G20735−2.8631.025−2.793
cela1_red_10_25661750FemaleA/A (Intercept)68820825.9790.3672.1146.34e-10
A/G168482.0260.563.619
G/G7213.6842.3865.736
MaleA/A (Intercept)4116522.130.36760.3450.399
A/G57140.9340.691.353
G/G1420.3451.5120.228
HaplotypeFemaleA/A (Intercept)69020825.9050.36471.1257.29e-09
AGGAGAGAAGA/B160462.3870.5734.166
B/B1348.7011.735.029
MaleA/A (Intercept)4066622.0170.3661.1530.037
A/B62131.720.6692.571
B/B1420.5061.4920.339
HaplotypeFemaleA/A (Intercept)79524226.5910.45158.9280.026
AGAGAAGAGAA/B6816−2.2441.005−2.233
MaleA/A (Intercept)4818022.2790.35163.4030.775
A/B11−1.1223.925−0.286