Table 4 Effect sizes for the most highly associated GWAS SNPs and for the AGGAGAGAAG haplotype at the most highly associated regional heritability region. Models were run for each sex separately and included a pedigree relatedness as a random effect. Count and ID Count indicate the number of ACC measures and the number of unique individuals for each genotype, respectively. Wald.P indicates the P-value for a Wald test of genotype as a fixed effect

Locus	Sex	Genotype	Count	ID Count	Solution	S.E.	Z Ratio	Wald.P
cela1_red_10_26005249	Female	A/A (Intercept)	98	28	29.575	0.732	40.43	3.43e-06
		A/G	388	114	−3.269	0.733	−4.46
		G/G	377	116	−3.888	0.786	−4.944
	Male	A/A (Intercept)	27	6	24.405	0.964	25.327	8.90e-03
		A/G	248	40	−1.813	0.993	−1.826
		G/G	207	35	−2.863	1.025	−2.793
cela1_red_10_25661750	Female	A/A (Intercept)	688	208	25.979	0.36	72.114	6.34e-10
		A/G	168	48	2.026	0.56	3.619
		G/G	7	2	13.684	2.386	5.736
	Male	A/A (Intercept)	411	65	22.13	0.367	60.345	0.399
		A/G	57	14	0.934	0.69	1.353
		G/G	14	2	0.345	1.512	0.228
Haplotype	Female	A/A (Intercept)	690	208	25.905	0.364	71.125	7.29e-09
AGGAGAGAAG		A/B	160	46	2.387	0.573	4.166
		B/B	13	4	8.701	1.73	5.029
	Male	A/A (Intercept)	406	66	22.017	0.36	61.153	0.037
		A/B	62	13	1.72	0.669	2.571
		B/B	14	2	0.506	1.492	0.339
Haplotype	Female	A/A (Intercept)	795	242	26.591	0.451	58.928	0.026
AGAGAAGAGA		A/B	68	16	−2.244	1.005	−2.233
	Male	A/A (Intercept)	481	80	22.279	0.351	63.403	0.775
		A/B	1	1	−1.122	3.925	−0.286