Table 1 Top 10 enriched KEGG pathways in the selected genes
PathwayGenes Involved in PathwayP-Value
1Lysine degradationLONP2,IQCk, ATPBD4,PPP1R1C,ARIH1,AAED18.30E−06
2AlcoholismH2A.1, H2AFJ,H4, H3.1,CAMKK2, H2B.1B0.000569
3Systemic lupus erythematosusH2A.1, H2AFJ,H4, H3.1,H2B.1B0.000907
4Cytosolic DNA-sensing pathwayPOLR2F,STING,IL330.015158
5Adipocytokine signaling pathwayIRS2,STK11, CAMKK20.021361
6Cardiac muscle contractionUQCR11,OK/SW-CL.16,MYO7A0.027874
7Parkinson’s diseaseUQCR11,OK/SW-CL.16,PINK1, MYO7A0.037931
8Pyrimidine metabolismPOLR2F, TS, NME50.051757
9Sphingolipid metabolismUGT8, PLPP30.060316
10Huntington’s diseasePOLR2F, UQCR11,OK/SW-CL.16, MYO7A0.074228