Table 1 Variants detected by whole-genome resequencing of one affected Malinois puppy (MA163)
Filtering StepNumber of Variants
Variants in the whole genomea1,889,727
Variants in the critical 10.6 Mb interval on chromosome 575,231
Variants in the critical interval that were absent from 146 other dog genomes37
Protein-changing variants in the whole genomea7936
Protein-changing variants in the 10.6 Mb critical interval on chromosome 5817
Protein-changing variants in the critical interval, absent from 146 other dog genomes0
  • a The sequences were compared to the reference genome (CanFam 3.1) from a Boxer. Protein-changing variants were classified based on the ENSEMBL annotation (version 72).