Table 1 List of top detoxification genes significantly overexpressed in pyrethroid resistant An. funestus in Uganda for all comparisons
ProbeTranscriptAn. gambiae IDR-CR-SC-SDescription
CUST_12777_PI426302897Afun012777 CYP4C27AGAP009246-PA3.610.36.8Cytochrome p450
CUST_8293_PI426302897Afun008293AGAP008291-PA187.883.0Trypsin-related protease
CUST_7663_PI426302897Afun007663 (CYP6M7)AGAP008213-PA70.124.0Cytochrome p450
CUST_13921_PI426302897Afun013921AGAP006709-PA64.449.5Chymotrypsin 1
CUST_500_PI426302897Afun000500NA27.123.0Glycogenin
CUST_9227_PI426302897Afun009227AGAP008141-PA22.821.2Argininosuccinate lyase
CUST_7769_PI426302897Afun007769 (CYP9K1)AGAP000818-PA21.516.1Cytochrome p450
CUST_15331_PI426302897Afun015331 (CYP307A1)AGAP001039-PB16.63.9Cytochrome p450
CUST_11042_PI426302897Afun011042AGAP003321-PA13.38.1Glycine dehydrogenase
CUST_13870_PI426302897Afun013870AGAP012697-PA11.914.8Sulfotransferase
CUST_295_PI406199798AGAP000177-RAAGAP000177-RA10.58.0Cuticle protein 7
CUST_4223_PI426302897Afun004223 (CYP4H17)AGAP008358-PA10.17.5Cytochrome p450
CUST_15523_PI426302897Afun015523AGAP010581-PA8.15.7abc transporter
CUST_4631_PI406199798AGAP005698-RAAGAP005698-RA7.63.5Cuticular protein 4
CUST_1458_PI406199769combined_c7386.74.9Short-chain dehydrogenase
CUST_13481_PI426302897Afun013481 (GSTe1)AGAP009195-PA6.65.6Glutathione-s-transferase
CUST_3246_PI426302897Afun003246AGAP006220-PA6.54.5Aldehyde oxidase
CUST_8354_PI426302897Afun008354 (GSTD3)AGAP004382-PA6.55.1Glutathione transferase
CUST_12343_PI426302897Afun012343 (CYP4H17)AGAP008358-PA6.04.4Cytochrome p450 4d1
CUST_11963_PI426302897Afun011963AGAP006220-PA5.74.0Aldehyde oxidase
CUST_11037_PI426302897Afun011037AGAP003581-PA5.78.0Alcohol dehydrogenase
CUST_376_PI406199788gb-CYP4H255.45.3Cytochrome p450
CUST_12197_PI426302897Afun012197 (CYP304B1)AGAP003066-PA5.23.3Cytochrome p450
CUST_7127_PI426302897Afun007127 (CYP4C36)AGAP009241-PA5.22.6Cytochrome p450
CUST_6930_PI426302897Afun006930 (CYP6M2)AGAP008212-PA5.15.3Cytochrome p450
CUST_7861_PI426302897Afun007861 (CYP6Z1)AGAP008219-PA4.82.5Cytochrome p450
CUST_10949_PI426302897Afun010949AGAP010887-PA4.67.4Cuticular protein rr-1 family
CUST_7696_PI406199798AGAP008141-RAAGAP008141-RA4.62.2Argininosuccinate lyase
CUST_3731_PI406199772CD577517.14.24.7Cuticle protein
CUST_7369_PI426302897Afun007369 (CYP6P9a)AGAP002865-PA4.23.0Cytochrome p450
CUST_13871_PI426302897Afun013871AGAP012697-PA4.12.3Sulfotransferase
CUST_13273_PI406199769combined_c6791 (CYP9J11)AGAP012296-PA4.13.6Cytochrome p450
CUST_12461_PI426302897Afun012461AGAP000288-PA4.16.8Alcohol dehydrogenase
CUST_7722_PI426302897Afun007722AGAP009850-PA4.03.6Abc transporter
CUST_10360_PI426302897Afun010360AGAP006222-PA4.03.2UDP glucosyl transferases
CUST_9866_PI426302897Afun009866 (GSTe5)AGAP009192-PA3.92.7Glutathione-s-transferase
CUST_9492_PI426302897Afun009492AGAP001722-PA3.88.8Carboxylesterase
CUST_7469_PI426302897Afun007469 (CYP9J11)AGAP012296-PA3.83.0Cytochrome p450
CUST_15244_PI426302897Afun015244AGAP000820-PA3.75.9Cuticular protein rr-1 family
CUST_10836_PI426302897Afun010836AGAP006228-PA3.42.3Esterase b1
CUST_484_PI406199788gb-CYP9J33.32.1Cytochrome p450
CUST_12666_PI426302897Afun012666 (CYP315A1)AGAP002429-PA3.23.7Cytochrome p450
CUST_405_PI406199788gb-CYP6AD13.22.0Cytochrome p450
CUST_9027_PI426302897Afun009027AGAP009463-PA3.12.1Abc transporter
CUST_9335_PI426302897Afun009335AGAP003343-PA3.12.8Cytochrome p450
CUST_720_PI406199788gb-PX4B3.12.8Oxidase peroxidase
CUST_10630_PI426302897Afun010630 (CYP6P5)AGAP002866-PA3.16.3Cytochrome p450
CUST_45_PI426302897Afun000045 (GSTe2)AGAP009194-PA2.92.1Glutathione-s-transferase gst
CUST_10994_PI426302897Afun010994 (CYP6P4)AGAP002867-PA2.83.2Cytochrome p450
CUST_30_PI426302915CYP6Z32.82.4Cytochrome p450
CUST_3315_PI406199769combined_c16752.72.6UDP glucosyl transferases
CUST_8909_PI426302897Afun008909 (CYP4K2)AGAP002416-PA2.73.0Cytochrome p450
CUST_35_PI406199775COEAE6OAGAP002863-PA2.63.1Carboxylesterase
CUST_7499_PI426302897Afun007499 (GSTD1-5)AGAP004164-PA2.52.1Glutathione transferase
CUST_9584_PI426302897Afun009584 (CYP6M4)AGAP008214-PA2.33.2Cytochrome p450
CUST_3394_PI426302897Afun003394 (CYP325A1)AGAP000284-PA2.12.1Cytochrome p450