Table 2 Summary of phenotypes for HEM25 SLC25 family genetics interactors
GrowthHeme Level (% WT)ETC Complex Stability
StrainGlycine as N Sourcehem 25ΔDextrose as C Sourcehem 25ΔLactate as C Sourcehem25ΔHeme Contenthem25ΔIhem25ΔIIhem25ΔIIIhem25ΔIVhem25ΔVhem25Δ
Wild type++++a+++++++100+++++++++++++++
hem25Δ++++++++++35++++++++++++
flx1Δ+++++++++++++b4910++++++++++++++++++++++++++
mtm1Δ++++++++c2219
ort1Δ++++++++d425
sfc1Δ+++++++++++++++bb408
pet8Δ+++++++++b388
aac3Δ+++++++++++++++++++++15057
  • a Relative level.

  • b Alleviated by glycine and 5-Ala.

  • c Alleviated by 5-Ala.

  • d Alleviated by glycine.