Table 1 Probability of an observed nucleotide read as a function of the individual genotype g and error rate ε
GenotypeNucleotide Read
1 (MM)FormulaFormulaFormulaFormula
2 (Mm)FormulaFormulaFormulaFormula
3 (mm)FormulaFormulaFormulaFormula
  • M and m denote candidate alleles (the two most abundant nucleotide reads in the population sample, e.g., C and T) and e1 and e2 denote other nucleotide reads (e.g., in this case, A and G).