Table 3 Significant genetic correlation across covariate-adjusted organohalogen serum levels and corresponding linear correlation
Maternal GeneticsFetal GeneticsM/F rg
CompoundCompoundNrg (SE)rresrgrres PaNrg (SE)P-ValueaMrgFrg Pb
BDE-28BDE-1006980.92*** (0.08)0.77***<0.01649NCNDND
BDE-28BDE-1536970.34*** (0.29)0.56***2.1 × 10−76480.66*** (0.21)3.4 × 10−31.1 × 10−15
BDE-47BDE-997410.98*** (0.04)0.93***<0.01688NCNDND
BDE-47BDE-1007501.00*** (0.04)0.93***<0.01697NCNDND
BDE-47BDE-1537490.61* (0.18)0.65***NS6960.77*** (0.09)3.4 × 10−63.6 × 10−9
BDE-99BDE-1007410.99*** (0.07)0.88***<0.01688NCNDND
BDE-99BDE-1537400.34*** (0.31)0.60***9.7 × 10−126870.66*** (0.22)NS2.2 × 10−16
BDE-100BDE-1537490.64*** (0.16)0.82***1.4 × 10−14696NCNDND
PCB180PCB138/1587521.00*** (0.40)0.81***<0.01698NCNDND
PCB180PCB1877140.80*** (0.33)0.86***2.4 × 10−4664NCNDND
  • rg, genetic correlation; SE, standard error; rres, significant Spearman’s linear correlation across residual congener levels after covariate adjustment; P, P-value; M/F, maternal/fetal; NS, not significant; NC, not converged; ND, not done. *** P < 0.001, ** P < 0.01, * P < 0.05.

  • a Fisher’s z transformation test between residual and genetic correlation coefficients.

  • b Fisher’s z transformation test between maternal genetic and fetal genetic correlation coefficients.