Table 4 Genome-wide and nominally significant association of maternal chr9:rs11789653 and chr19:rs7259965 across congeners
chr19:rs7259965 – MAF = 0.29chr9:rs11789653 – MAF = 0.025
CompoundNβSEP-ValueNβSEP-Value
Persistent pesticides
 p,p′-DDE7590.320.057.8 × 10−117620.320.152.9 × 10−2
 Polybrominated diphenyl ethers
 BDE-286950.140.047.0 × 10−46980.650.123.2 × 10−8
 BDE-477590.230.061.6 × 10−47620.680.178.8 × 10−5
 BDE-997380.320.062.1 × 10−87410.50.174.7 × 10−3
 BDE-1007470.280.063.9 × 10−67500.660.182.9 × 10−4
 BDE-1537460.110.06NS7490.520.183.4 × 10−3
 Sum PBDE7070.240.058.2 × 10−67150.590.163.1 × 10−4
Polychlorinated biphenyls
 PCB1187110.060.03NS7150.20.13.7 × 10−2
 PCB1537520.040.03NS7550.210.13.0 × 10−2
  • In each category, the results are shown in alphanumeric order. The genome-wide significant associations are shown in bold and the suggestively significant associations are in italics. Genome-wide association threshold is P = 5 × 10−8 and suggestive association threshold is P = 5 × 10−6. MAF, minor allele frequency; SE, standard error; NS, not significant.