Table 2 Genetic variants in the CD55 gene detected in 1734 Ghanaian children
SNP IDPosition Chr1 (Build 37)Relative PositionaAmino Acid ExchangeNovelMAF Cases (N = 831)MAF Controls (N = 903)Polyphen2 PredictionbSIFT Predictionc
1rs6685886207,494,218−893C > A0.270.23
2rs28371586207,494,913−198C > G0.020.03
3rs879066510207,495,089−21C > GYes-0.0006
4rs7542430207,495,116c.6C > GT2T0.010.02
5rs28371587207,495,224c.100 + 14C > T0.0020.002
6rs28371588207,495,781c.155G > TR52H0.040.04BenignTolerated
7rs147474393207,495,871c.245T > GL82R0.0080.01BenignTolerated
8rs28371603207,497,911c.294C > TC98C0.0050.007
9rs2564979207,498,939c.479-28T > A0.030.04
10rs150286783207,500,169c.651G > AL217L-0.0005Tolerated
11rs878953964207,504,465c.677C > TP226LYesSingletonProbably damagingTolerated
12rs60822373207,504,467c.679G > CA227PSingletonProbably damagingTolerated
13rs566298946207,504,537c.749C > TT250MSingletonProbably damagingDamaging
14rs756597715207,510,066c.882A > GP294PSingleton
15rs779822800207,510,067c.883A > GT295ASingletonPossibly damagingTolerated
16rs879028717207,510,084c.900T300TYesSingleton
17rs774684822207,510,665c.980-9A > GSingleton
18rs116473488207,510,691c.997G > AV333I0.020.02BenignTolerated
19rs550337244207,510,708c.1014G > AK338K0.0010.002
20rs150172588207,510,725c.1031C > TT344I0.0030.003Possibly damagingTolerated
21rs28371628207,512,734c.1081-8G > A0.080.07
22rs542054808207,513,741c.1081 + 979C > TSingleton
23rs879071049207,513,772c.1081 + 1010G > AYesSingleton
24rs138016651207,513,861c.1081 + 1099C > T0.0050.007
25rs375489214207,532,908c.1099T > CV406ASingletonn.a.Tolerated
26rs878906671207,532,925c.1117G > TD412YYESSingletonn.a.Damaging