Table 2 Rescue of GATOR1 mutants’ lethality
CrossGenotype (Number of Adult Flies)% of Expected Ratio
nprl21; UAS-Nprl2 (male) × nprl21/FM7; Ubi-GAL4 (Female)nprl21/FM7;Ubi > Nprl2 (Female)nprl21; Ubi > Nprl2 (Female)111.6a
155173
Ubi-GAL4; nprl31/TM3 × UAS-Nprl3; nprl31/TM3Ubi > Nprl3; nprl31/TM3Ubi > Nprl3; nprl31109.3b
302165
iml1-Iml1/SM6; iml11/TM3 × iml11/TM3iml1-Iml1; iml11/TM3iml1-Iml1; iml11102.0c
394201
Ubi-GAL4; nprl31/TM3 × UAS-Nprl3; Df/TM3Ubi > Nprl3; nprl31/TM3 and Ubi > Nprl3; Df/TM3Ubi > Nprl3; nprl31/Df113.6b
405230
iml1-Iml1/SM6; iml11/TM3 × Df/TM3iml1-Iml1; iml11/TM3 and Iml1; Df/TM3iml1-Iml1; iml11/Df106.7c
283151
nprl21; TorAV/SM6 (Male) × nprl21/FM7 (Female)nprl21/FM7;TorAV/+ (Female)nprl21; TorAV/+ (Female)89.7d
290260
TorAV/SM6; nprl31/TM3 × TorAV/SM6; Df/TM3TorAV/+; nprl31/TM3 and TorAV/+; Df/TM3TorAV/+; nprl31/Df90.7c
344156
CG-GAL4; nprl31/TM3 × UAS-Nprl3; Df/TM3CG > Nprl3; nprl31/TM3 and CG > Nprl3; Def/TM3CG > Nprl3; nprl31/Df125.3b
241151
  • a In these crosses, the FM7 (first chromosome balancer) was identified by the Bar eye. The expected Medelian ratio of non-Bar eyes to Bar eye female flies was 1:1.

  • b In these crosses, the TM3 (third chromosome balancer) was identified by the Sb marker. The expected Medelian ratio of non-Sb to Sb flies was 1:2, since the TM3/TM3 is embryonic lethal.

  • c In these crosses, the SM6 (second chromosome balancer) and TM3 was identified by the Cy and Sb markers. The expected Medelian ratio of non-Cy and non-Sb to non-Cy and Sb flies was 1:2, since the TM3/TM3 is embryonic lethal.

  • d In these crosses, the FM7 and SM6 was identified by the Bar and Cy markers. The expected Medelian ratio of non-Cy and non-Bar to non-Cy and Bar female flies was 1:1.