Table 3 Overlap of mRNAs that are bound by BRAT and PUM and those that are stabilized in a miR-309 family deletion mutant
DatasetNumberOverlapP ValueaOdds Ratio
Expressed genes for BRAT and PUM RIP (0–3 hr)6191
BRAT-RIP genes (0–3 hr, 5% FDR)11974251.1 × 10−151.75
PUM-RIP genes (0–3 hr, 5% FDR)6412657.4 × 10−192.18
miRNA-target genes without Smaug-IP-genes1622
Expressed genes for BRAT and PUM RIP (0–3 hr)6191
BRAT-RIP genes (0–3 hr, 5% FDR)11971071.1 × 10−61.82
PUM-RIP genes (0–3 hr, 5% FDR)641370.570.98
miR-309 cluster-dependent unstable mRNAs (2–3 hr)363
  • BRAT, Brain tumor; PUM, Pumilio; FDR, false discovery rate; miRNA, microRNA.

  • a One-tailed Fisher’s exact test.