Table 2 LET-23 EGFR and LET-60 Ras induce ectopic uv1 specification
GenotypeNo. of GFP-Positive uv1 CellsAverage No. of uv1 Cells Specifiedn
7654
Wild-type (strain BL5715)00060460
let-23(sa62gf) (strain HV760)018494.17*58
let-60(n1046gf) (strain HV285)12955514.85***136
itr-1(sy290gf) (strain HV651)0001114111
let-60(n1046gf) itr-1(sy290gf) (strain HV623)13871195.16**,***129
  • n, number of animals examined.

  • * P < 0.005.

  • ** P < 0.001, Student’s t-test, comparison to let-60(n1046gf).

  • *** P < 0.001, Student’s t-test, comparisons to wild type.