Table 3 Association of LPCAT1 rs115960372 with human macrophage expression of 28 OXPHOS genes
GeneProbesChrProbe_StartProbe_EndβaSEMP Value
M19 OXPHOS genes
 SDHBILMN_1667257117,476,54117,476,5900.0240.01350.080
 NDUFB3ILMN_21199452201,943,702201,944,7020.0450.01686.82 × 10−3
 COX17ILMN_21877183119,396,160119,396,2090.0000.01950.982
 ATP5IILMN_17725064678,058678,1070.01440.01250.250
 UQCRQILMN_16664715132,174,747132,174,7960.0130.01520.389
 COX7A2ILMN_1701293675,950,94375,951,9430.0190.01450.182
 ATP5J2ILMN_2307883799,217,92999,217,9780.0280.01560.075
 NDUFB2ILMN_21173307140,402,713140,402,762−0.0080.01720.635
 COX6CILMN_16541518100,904,152100,904,2010.0060.01160.611
 COX8AILMN_18094951163,742,26363,743,2630.0200.01520.183
 NDUFA9ILMN_1760741124,796,1514,796,2000.0400.01750.021
 ATP5G2ILMN_16605771254,063,07154,063,120−0.0270.01850.137
 COX6A1ILMN_178363612120,876,242120,876,2910.0240.01640.146
 NDUFA11ILMN_2175712195,945,9525,946,001−0.0180.01620.259
 NDUFB7ILMN_18136041914,816,06814,817,068−0.0020.01590.876
 COX6B1ILMN_21546711936,139,23236,139,281−0.0190.01320.150
 ATP5JILMN_23480932128,180,16828,180,217−0.0100.01540.509
 NDUFA1ILMN_1784286X119,005,887119,005,9360.0170.01390.232
M15 OXPHOS genes
 ATP5F1ILMN_17219891112,003,559112,003,6080.0330.01300.0110
 PPA2ILMN_16877854106,292,029106,293,0290.0460.02050.0256
 NDUFC1ILMN_17336034140,216,254140,217,2540.0500.01754.70 × 10−3
 NDUFA4ILMN_1751258711,006,66811,006,7170.0330.01710.0522
 ATP5C1ILMN_1701269107,801,0697,801,1180.0740.01835.64 × 10−5
 SDHDILMN_169848711111,966,144111,966,1930.0490.02010.015
 ATP5LILMN_207928511118,280,301118,280,3500.0490.0220.029
 NDUFAB1ILMN_21790181623,684,93423,684,9830.0910.01902.12 × 10−6
 ATP5HILMN_16663721775,524,60775,524,6560.0290.01360.031
 NDUFV2ILMN_2086417189,126,8719,127,8710.1040.01701.89 × 10−9
  • a Effect of the minor rs115960372 T allele on gene expression. Its allele frequency was 0.10 and its r2 imputation quality was 0.86.