Table 5 Association of PARK2 rs192804963 with human macrophage expression of 28 OXPHOS genes
GeneProbesChrProbe_StartProbe_EndβaSEMP Value
M19 OXPHOS genes
 SDHBILMN_1667257117,476,54117,476,5900.0270.01160.021
 NDUFB3ILMN_21199452201,943,702201,944,7020.0720.01435.22 × 10−7
 COX17ILMN_21877183119,396,160119,396,2090.0640.01671.36 × 10−4
 ATP5IILMN_17725064678,058678,1070.0420.01079.34 × 10−5
 UQCRQILMN_16664715132,174,747132,174,7960.0350.01318.31 × 10−3
 COX7A2ILMN_1701293675,950,94375,950,9430.0550.01238.29 × 10−6
 ATP5J2ILMN_2307883799,217,92999,217,9780.0610.01335.13 × 10−6
 NDUFB2ILMN_21173307140,402,713140,402,7620.0350.01479.62 × 10−3
 COX6CILMN_16541518100,904,152100,904,2010.0550.00984.27 × 10−8
 COX8AILMN_18094951163,742,26363,743,2630.0560.01281.74 × 10−5
 NDUFA9ILMN_1760741124,796,1514,796,2000.0580.01521.08 × 10−4
 ATP5G2ILMN_16605771254,063,07154,063,1200.0240.01590.128
 COX6A1ILMN_178363612120,876,242120,876,2910.0710.01393.81 × 10−7
 NDUFA11ILMN_2175712195,945,9525,946,0010.0270.01390.055
 NDUFB7ILMN_18136041914,816,06814,817,0680.0260.01370.055
 COX6B1ILMN_21546711936,139,23236,139,2810.0220.01140.053
 ATP5JILMN_23480932128,180,16828,180,2170.0230.01320.086
 NDUFA1ILMN_1784286X119,005,887119,005,9360.0310.01190.010
M15 OXPHOS genes
 ATP5F1ILMN_17219891112,003,559112,003,6080.0330.01123.32 × 10−3
 PPA2ILMN_16877854106,292,029106,293,0290.0000.01780.967
 NDUFC1ILMN_17336034140,216,254140,217,2540.0260.01520.085
 NDUFA4ILMN_1751258711,006,66811,006,7170.0510.01464.65 × 10−4
 ATP5C1ILMN_1701269107,801,0697,801,1180.0280.01600.079
 SDHDILMN_169848711111,966,144111,966,1930.0270.01740.122
 ATP5LILMN_207928511118,280,301118,280,3500.0090.01920.655
 NDUFAB1ILMN_21790181623,684,93423,684,9830.0520.01651.86 × 10−3
 ATP5HILMN_16663721775,524,60775,524,6560.0200.01180.083
 NDUFV2ILMN_2086417189,126,8719,127,8710.0440.01503.52 × 10−3
  • a Effect of the minor rs192804963 A allele on gene expression. Its allele frequency was 0.21 and its r2 imputation quality was 0.66.