Table 1 Postnatal lethality and laterality defect
AgeP0–P1aP10P21
Dnaaf1m4BeiObservedbExpectedObservedcExpectedObserveddExpected
 Wild-type2920.52117.5128.25
 Heterozygote394143352116.5
 Homozygote1420.5617.508.25
Laterality defect8 (57.1%)2 (33.3%)N/Ae
 Situs inversus30
 Heterotaxy52
Lrrc48m6BeiObservedExpectedObservedExpectedObservedExpected
 Wild-type21182419.752217.75
 Heterozygote33363639.53135.5
 Homozygote18181919.751817.75
Laterality defect2 (11.1%)1 (5.3%)N/Ae
 Situs inversus20
 Heterotaxy01
  • N/A, not applicable.

  • a Only one litter was P0 out of total 11 litters.

  • b Chi-square test, P = 0.0583 (two-tailed).

  • c Chi-square test, P = 0.0065 (two-tailed).

  • d Chi-square test, P = 0.0037 (two-tailed).

  • e Laterality defect was not examined at P21.