Table 1 Suppression of glp-1(q231ts) by ubr-5 deletion alleles at 20°
GenotypeAvg. No. Embryos Produced per Brood% Viablen
unc-32 glp-1(q231ts)129 ± 8a016
ubr-5(om2);unc-32 glp-1(q231ts)174 ± 104010
ubr-5(ok1108);unc-32 glp-1(q231ts)189 ± 63414
  • Full broods were counted for the indicated (“n”) number of hermaphrodites, including both viable and nonviable embryos.

  • a The baseline No. of embryos produced by unc-32 glp-1(q231ts) controls in these experiments was substantially higher than previously reported (e.g., Maine and Kimble 1989, 1993). Controls were performed with two strains, both of which had been frozen since the early 1990s and were thawed specifically for these assays (see Materials and Methods). As described in Maine and Kimble (1993), ∼98% of unc-32 glp-1(q231ts) controls produced some (nonviable) embryos, and only ∼2% were Glp-1 sterile. >99.9% of ubr-5(-);glp-1(q231ts) animals produced embryos.