Table 1 The top seven novel regulators of border cell specification/migration identified in this study
Name of the
Candidate GenePredicted Effect on STAT Activity in Cell CultureScreened RNAi Lines Penetrance of the Phenotype Caused by the RNAi, %
CG8636 (translation initiation factor)Positive (Baeg et al. 2005)v28937Not viable
v10532562.35
GLC014302.20
Ptp61F (Protein tyrosine phosphatase)Negative (Baeg et al. 2005)HMS0042148.30
Negative (Müller et al. 2008)v3743640.50
v3743747.70
α-Snap (soluble NSF attachment protein)Positive (Baeg et al. 2005)v101341Not viable
JF0326646.60
v2237938.50
HMS00872None
HM0401931
brm (brahma)Negative (Baeg et al. 2005)v3772014.85
Positive (Müller et al. 2008)v3772115.80
GL00090None
HMS00050None
Fer3HCH (ferritin 3heavy chain homolog)v4050530.70
Positive (Müller et al. 2008)HMC03397None
mib2 (mind bomb 2)Negative (Müller et al. 2008)v4007926.75
CG12484 (immunoglobulin superfamily)Positive (Baeg et al. 2005)v2557618.60
v1048142.30
  • Listed based on the severity of the phenotype using a c306-Gal4 driver, with the strongest candidate (the highest penetrance) at the top. For novel genes, the predicted functions or conserved domains are given in parentheses.