Table 6 The least-squares regressions of frequencies of individuals bearing the reduced networks 70_4R1 and 65_2R4 in our data set and in the HapMap data set
Network/SNPDatasetGenesInterceptSlopeQuadratic TermR2
70_4R1 – AfOursVDR0.854n.s.n.s.0.18
70_4R1 – AfHapMapVDR0.633n.s.n.s.0.51
65_2R4OursVDR, MC1R, SLC24A50.4840.0129**–0.0007**0.85
65_2R4 – AfOursVDR, MC1R, SLC24A50.6980.0042*n.s.0.54
65_2R4HapMapVDR, MC1R, SLC24A50.021n.s.n.s.0.48
65_2R4 – AsHapMapVDR, MC1R, SLC24A50.0460.0183**n.s.0.90
65_2R4 – AsAllVDR, MC1R, SLC24A50.2710.0189***–0.0005**0.89
65_2R4 – Af – AsAllVDR, MC1R, SLC24A50.6930.0044**n.s.0.65
  • * Significant with P ≤ 0.05, ** significant with P ≤ 0.01, *** significant with P ≤ 0.001. SNP, single nucleotide polymorphism; n.s., not significant; – Af, the sub-Saharan populations have been excluded; – As, the Chinese and Japanese populations have been excluded.