Table 4 F. circinatum potentially unique candidate genes with known putative domains, indicating putative protein families and domains, the top predicted subcellular localization, and whether proteins are antigens or nonantigens
Name of Gene in FSP34PfamaCDDbSignalPcWoLF PSORTdVaxijene
FCIRG_07223Oxidored_FMNOYE_like_FMNNcytoNonantigen
TIM_phosphate_binding superfamily
NAD_binding_8 superfamily
NemA
FCIRG_00789Fungal_trans_2Fungal_trans_2 superfamilyNplasAntigen
RTA1RTA1 superfamily
FCIRG_05207RR_TM4-6Ncyto_nuclNonantigen
DUF4337
IFP_35_N
FCIRG_05759DUF2935Ncyto_nuclAntigen
FCIRG_03368DPBB_1PAT1YextrAntigen
FCIRG_03489TcdA_TcdB_poreTcdA_TcdB_pore superfamilyNmitoAntigen
Pfam-B_4370
Pfam-B_8938
FCIRG_14908HETHET superfamilyNmitoAntigen
FCIRG_12843Lysine_decarboxLysine_decarbox superfamilyNcytoAntigen
FCIRG_15130Pfam-B_12758NnuclAntigen
FCIRG_12122MMR_HSR1Ras_like_GTPase superfamilyNnuclNonantigen
FCIRG_13499Elong_Iki1YextrNonantigen
FCIRG_10116Peptidase_S8Peptidases_S8_S53NnuclAntigen
FCIRG_06189Pfam-B_19120ZnF_C2HCNnuclAntigen
FCIRG_05800Pfam-B_360Abhydrolase_6NnuclAntigen
FCIRG_03074DDRNBD_sugar-kinase_HSP70_actin superfamilyNcyskAntigen
FCIRG_10765MFS_1HpaXNplasNonantigen
FCIRG_04655tail_TIGR02242 superfamilyNcyto_nuclAntigen
FCIRG_02555AldedhNBD_sugar-kinase_HSP70_actin superfamilyNcytoAntigen
FCIRG_09038ADIPNnuclAntigen
  • a Protein family as predicted by the program Pfam.

  • b Conserved domains as predicted from the conserved domain database.

  • c Presence (Y) or absence (N) of signal peptides as predicted by the program SignalP.

  • d Top predicted subcellular localization of the putative proteins as predicted by the program WoLF PSORT.

  • e Predicted antigenicity or nonantigenicity of the putative proteins as predicted by the program Vaxijen.