Table 1 Scores for the top 59 mutants from genome-wide screen
ORFGene NameScreen 1Screen 2Average ScoreGenome Stabilitya
GOS1YHL031C0.120.240.18
SMI1YGR229C0.310.420.37
SRB2YHR041C0.410.410.41+
BUB1YGR188C0.210.190.20+
FBP26YJL155C0.090.240.17+
MPH1YIR002C0.210.260.24+
POL32YJR043C0.240.280.26+
LAS21YJL062W0.320.410.36
SWF1YDR126W0.000.030.02
TOP3YLR234W0.340.210.27+
VPS53YJL029C0.110.170.14+
UBP3YER151C0.390.240.32+
YDR455CYDR455C0.310.280.30
HHY1YEL059W0.290.330.31
RAD51YER095W0.150.450.30+
BST1YFL025C0.280.500.39
SPF1YEL031W0.330.470.40
RPO41YFL036W0.390.430.41
RPL19BYBL027W0.260.200.23
MRC1YCL061C0.370.190.28
SLX5YDL013W0.370.360.37+
PER1YCR044C0.190.460.32+
RIC1YLR039C0.330.230.28
SWI6YLR182W0.200.330.27
YJL175WYJL175W0.180.490.33
BUB3YOR026W0.100.170.13
DIA2YOR080W0.320.360.34+
PAP2YOL115W0.270.320.29+
VAM3YOR106W0.200.350.27
VAM10YOR068C0.170.420.30
SHE4YOR035C0.250.400.32
TLG2YOL018C0.410.490.45
YPT6YLR262C0.220.170.20
ARC1YGL105W0.180.290.24
COG8YML071C0.190.200.20+
YMR031W-AYMR031W-A0.130.080.10
YNL171CYNL171C0.370.210.29
YMR166CYMR166C0.140.480.31
COG6YNL041C0.200.300.25
SAC1YKL212W0.000.050.02
CPS1YJL172W0.330.500.41
RPE1YJL121C0.070.270.17
HTZ1YOL012C0.410.480.44
JHD2YJR119C0.310.320.32+
DPB3YBR278W0.410.420.41
EAF1YDR359C0.290.130.21+
MNN10YDR245W0.120.130.13+
PPH3YDR075W0.310.190.25
SPT3YDR392W0.050.340.20+
SWI4YER111C0.190.180.19
SNX4YJL036W0.290.240.26+
ASC1YMR116C0.140.210.17
COG7YGL005C0.140.280.21+
VAM7YGL212W0.000.210.11
DBF2YGR092W0.120.460.29+
CKB1YGL019W0.270.470.37
LEA1YPL213W0.400.240.32
VPS1YKR001C0.000.000.00
ERG3YLR056W0.380.270.33
  • a Genome stability (+) indicates that the respective gene has been reported to have function(s) in pathway(s) important for maintaining genome integrity.