Table 1 Association results for SBP-associated genes with gene-based P < 2.3×10−6
GeneP_GeneLocusSNPbP_CADScore
PositionReportedaIDFeatureP_SNP
CLCN64.79E-091p36NPPBrs17367504intronic2.11E-105
NPPA1.60E-061p36.21rs50683UTR1.86E-078
MTHFR2.74E-091p36.3MTHFRrs17367504intronic2.11E-107
FGF52.18E-074q21FGF5rs16998073upstream2.84E-085
C10orf1071.44E-0610q21.2C10orf107rs4590817intronic5.95E-082
NT5C24.27E-0910q24.32NT5C2rs11191548downstream5.03E-105.10E-084
CYP17A14.58E-0910q24.32rs1004467intronic6.61E-103.13E-088
AS3MT5.89E-0910q24.32rs11191454intronic1.12E-097.02E-095
C10orf325.89E-0910q24.32rs3824754intronic9.75E-107.83E-092
CNNM25.39E-0910q24.32rs1926032intronic5.72E-106.71E-094
WBP1L1.26E-0710q24.32rs486955intronic9.47E-092
PLEKHA73.64E-0711p15.1PLEKHA7rs381815intronic2.45E-093
ATP2B12.62E-1112q21.3ATP2B1rs2681472intronic1.32E-125
SH2B37.71E-0912q24SH2B3rs3184504exonic1.69E-098.10E-117
ATXN26.07E-0912q24rs653178intronic9.3E-103.52E-087
FAM109A2.02E-0612q24rs37420043UTR1.01E-064.09E-062
HECTD42.01E-0712q24rs11066188intronic1.72E-081.63E-074
NAA254.12E-0712q24rs17696736intronic3.43E-081.88E-073
PTPN115.97E-0712q24rs11066320intronic4.56E-081.82E-0710
TRAFD18.62E-0812q24rs17630235downstream1.45E-081.41E-084
ULK32.41E-0715q24.1ULK3rs6495122downstream6.03E-083
CPLX31.09E-0715q24.1rs7162232intronic2.33E-085
CSK2.05E-0915q24.1rs1378942intronic3.43E-104
MIR45131.07E-0915q24.1rs1378942intronic3.43E-101
CYP1A21.93E-0615q24.1rs11854147downstream7.16E-075
LMAN1L4.23E-0815q24.1rs7176022intronic2.11E-082
FES4.40E-0715q26.1FESrs2521501intronic1.22E-075
FURIN1.38E-0615q26.1FURINrs8032315intronic3.02E-075.35E-106
ACBD45.59E-0717q21.31ZNF652rs12946454intronic8.91E-081
PLCD38.11E-0717q21.31rs12946454intronic8.91E-084
  • a Genes reported in this region by the ICBP GWAS.

  • b The most associated SNP within the corresponding gene identified by gene-based analysis.