Table 3 Summary of SOS values and mutation rates
Amino Acid PositionInsertion CompositionBasal SOSΔ Nalidixic Acid SOSnMedian Mutation RateUpper BoundaryLower Boundary
30IICLN1657 ± 108**1553 ± 204**47.63E-071.16E-063.27E-07
57LVFKQ1022 ± 42*2910 ± 262*45.52E-086.36E-082.45E-08
76CLNNK827 ± 752233 ± 166*35.90E-081.33E-073.75E-08
79CLNTF1220 ± 39**915 ± 111**61.56E-061.85E-066.32E-07
97ILFKQ1635 ± 284113 ± 485**49.05E-072.05E-061.62E-07
115KLFKH934 ± 116617 ± 119242.19E-094.50E-091.60E-09
125LFKHF960 ± 676552 ± 162084.36E-099.44E-092.46E-09
132V*1419 ± 199*629 ± 364**81.83E-062.19E-062.50E-07
143NSCLN908 ± 788580 ± 175676.21E-081.08E-073.71E-08
162LFKQL1211 ± 51**10,327 ± 1061**59.02E-091.12E-086.58E-09
196LFKQQ943 ± 465168 ± 62492.51E-094.31E-091.18E-09
208VFKHQ1006 ± 79−183 ± 42**43.04E-094.94E-091.32E-09
224AHV*1146 ± 83*1402 ± 144**81.67E-062.51E-069.16E-07
228CLNKA1085 ± 62*3167 ± 256*43.10E-081.07E-072.10E-08
232LFKQV1626 ± 95**1208 ± 249**46.89E-078.38E-074.91E-07
DnaQ928DnaQ928768 ± 432655 ± 422**64.74E-086.42E-083.90E-08
Q182AQ182A675 ± 251185 ± 864**31.42E-083.02E-085.51E-09
QLSLPLQLSLPL1204 ± 23**6944 ± 58566.44E-091.14E-084.58E-09
WTWT863 ± 415921 ± 649112.84E-093.61E-092.14E-09
ΔDnaQΔDnaQ1314 ± 73**527 ± 233**86.46E-079.79E-074.04E-07
  • P values are in comparison with wild-type (no drug or nalidixic acid). *P < 0.05 and **P < 0.005. Upper and lower boundary columns present 95% C.I.s of mutation rates determined using the Lea Coulson Method of Medians as described in Materials and Methods.