Table 4 Correlation between MTDR index and ribosomal load for the different tissues/conditions of the analyzed organisms
OrganismCorrelation Between MTDR Index and Ribosomal LoadCorrelation Between tAI Index and Ribosomal LoadCorrelation between CAI Index and Ribosomal Load
E. coli (Li et al. 2012)r = 0.63 p = 9.4*10−156r = 0.56 p = 1.3*10−117r = 0.60 p = 5.7*10−142
B. subtilis (Li et al. 2012)r = 0.58 p = 0r = 0.33 p = 0r = 0.56 p = 0
S. cerevisiae – Exponential (Ingolia et al. 2009),r = 0.53 p = 2.9*10−112r = 0.62 p = 5.5*10−163r = 0.65 p = 3*10−184
S. cerevisiae – Exponential (gb15) (Brar et al. 2012)r = 0.32 p = 1*10−22r = 0.29 p = 2.3*10−18r = 0.32 p = 1.3*10−22
S. cerevisiae – Exponential (A14201) (Brar et al. 2012)r = 0.80 p = 1.4**10−131r = 0.77 p = 7.9*10−116r = 0.80 p = 1.1*10−134
S. cerevisiae – DNA replication (Brar et al. 2012)r = 0.26 p = 1.9*10−8r = 0.11 p = 0.023r = 0.09 p = 0.048
S. cerevisiae – Recombination (Brar et al. 2012)r = 0.31 p = 2.4*10−12r = 0.20 p = 7.6*10−6r = 0.20 p = 1.4*10−5
S. cerevisiae – Metaphase II (Brar et al. 2012)r = 0.46 p = 4.3*10−8r = -0.12 p = 0.15r = -0.12 p = 0.18
S. cerevisiae – Anaphase (Brar et al. 2012)r = 0.23 p = 0.027r = 0.10 p = 0.31r = 0.11 p = 0.26
S. cerevisiae – Spore packing (Brar et al. 2012)r = 0.50 p = 0r = -0.15 p = 0.045r = -0.16 p = 0.029
S. cerevisiae – Spores (Brar et al. 2012)r = 0.35 p = 0.00015r = -0.11 p = 0.25r = -0.08 p = 0.39
C. elegans – L4 (Stadler et al. 2012)r = 0.53 p = 3.5*10−165r = 0.45 p = 1.8*10−112r = 0.49 p = 1.9*10−132
C. elegans – L2 (Stadler et al. 2012)r = 0.48 p = 1.6*10−197r = 0.47 p = 1.4*10−185r = 0.51 p = 1.4*10−219
C. elegans – L1 (Stadler et al. 2012)r = 0.51 p = 5.9*10−10r = 0.42 p = 2.8*10−72r = 0.46 p = 9.3*10−86
M. musculus – Embryonic stem cells(Ingolia et al. 2011)r = 0.02 p = 0.35r = 0.07 p = 0.0095r = 0.07 p = 0.0046
M. musculus – Neutrophils (Guo et al. 2010)r = 0.22 p = 1.2*10−13r = 0.07 p = 0.012r = 0.12 p = 5.4*10−5
M. musculus – Embryonic fibroblast (Lee et al. 2012)r = 0.41 p = 4.1*10−15r = 0.22 p = 3.6*10−5r = 0.22 p = 3.4*10−5
H. sapiens – HEK293 (Lee et al. 2012)r = 0.17 p = 1.9*10−9r = 0.15 p = 9.2*10−8r = 0.15 p = 3.4*10−8
  • MDTR, mean of the typical decoding rates; tAI, tRNA adaptation index; CAI, codon adaptation index.