Table 5 The most significant GO functions in high-quality APA genes with five or more PACs
GO_IDOntologyTermP value
GO:0004872molecular_functionReceptor activity3.24E-33
GO:0034660biological_processncRNA metabolic process1.16E-23
GO:0008236molecular_functionSerine-type peptidase activity3.95E-23
GO:0017171molecular_functionSerine hydrolase activity3.95E-23
GO:1901135biological_processCarbohydrate derivative metabolic process5.48E-23
GO:0006399biological_processtRNA metabolic process1.07E-21
GO:0006418biological_processtRNA aminoacylation for protein translation1.34E-18
GO:0043038biological_processAmino acid activation1.34E-18
GO:0043039biological_processtRNA aminoacylation1.34E-18
GO:0009056biological_processCatabolic process1.43E-17
GO:0004812molecular_functionAminoacyl-tRNA ligase activity5.44E-16
GO:0016875molecular_functionLigase activity, forming carbon-oxygen bonds5.44E-16
GO:0016876molecular_functionLigase activity, forming aminoacyl-tRNA and related compounds5.44E-16
GO:0003824molecular_functionCatalytic activity8.21E-16
GO:0016798molecular_functionHydrolase activity, acting on glycosyl bonds2.26E-12
GO:0004553molecular_functionHydrolase activity, hydrolyzing O-glycosyl compounds2.77E-12
  • GO, Gene Ontology; APA, alternative polyadenylation; PACs, poly(A) site clusters; ncRNA, noncoding RNA; tRNA, transfer RNA.