Table 1 Nucleotide divergence of heart enhancers, pseudogenes (neutral reference), control sequences, and HACNSs
Sequence RegionDivergence (per Kilobase)NIP-Value of Negative SelectionSNPs per kilobase
Human-SpecificNonhuman-Specific
Enhancers
 Proximal5.6660.010.779 × 10−505.61
 Tele5.4759.530.754 × 10−595.48
Others
 Neutral reference9.1474.919.65
 Controls6.4262.340.843 × 10−395.94
 HACNSs17.2429.754.7513.68
  • HACNSs, human accelerated conserved noncoding sequences; NI, neutrality index; SNP, single-nucleotide polymorphism.