Table 2 Elevated protein evolutionary rates in iron toxicity response genes in Malaysian yeast
PopulationRegulon Mean Ka/KsGenome Mean Ka/KsP
North American0.04870.08220.7511
West African0.18780.17770.3861
  • Each row reports analysis of the protein evolutionary rate, in one yeast population, of the set of genes upregulated in a ccc1 laboratory strain compared to wild-type during exposure to high-iron medium (Lin et al. 2011). P, the significance of a one-sided resampling test relative to the genomic null for a greater value of the mean, across genes of the iron toxicity response regulon, of ratios of nonsynonymous (Ka) to synonymous (Ks) coding sequence variants private to and fixed in the indicated yeast population.