Table 1 Red blood cell indices of wild-type, heterozygous, and homozygous hema6 mice
StrainRBC, 106/µLHGB, g/dLHCT, %MCV, flMCH, pgMCHC, g/dLRDW, %
wild-type9.2 ± 0.314.1 ± 0.443.2 ± 1.847.5 ± 0.515.4 ± 0.232.6 ± 0.316.6 ± 1.0
hema6/+10.3 ± 0.6**14.6 ± 0.743.9 ± 2.642.2 ± 0.4**14.2 ± 0.4**33.4 ± 0.8*16.0 ± 0.7
hema6/hema610.2 ± 0.5**14.2 ± 0.441.5 ± 1.740.8 ± 0.8**13.9 ± 0.4**34.2 ± 1.1**16.2 ± 0.6
  • Automated complete blood counts were obtained for six wild-type mice, five hema6/+, and nine hema6/hema6 mice at 6 wk of age; both male and female mice were used. Results are presented as mean ± SD. RBC, red blood cell; HGB, hemoglobin; HCT, hematocrit; MCV, mean corpuscular volume; MCH, mean corpuscular hemoglobin; MCHC, mean corpuscular hemoglobin concentration; RDW, red blood cell distribution width.

  • * P < 0.05, **P < 0.01, Student’s t test. Comparisons of hema6/+ and hema6/hema6 with wild-type mice were made, and the statistical significance was shown in the table.