Table 2 Significant and suggestive QTL identified by genome-wide scan of F2 mice
TraitQTLaChrPeak cM95% CILODbNearest markerSexHigh Strain; Inheritance
HDL cholesterolCq1c174.770.6−81.68.9rs13476229MFKK, Add
236.221.2−51.23.1rs3718711MI, Add
319.217.2−38.23.4rs6324747FI, Add
475.160.1−88.63.1UT_4_132.137715FKK, Add
624.89.8−44.82.9rs6355719MFKK, Dom
Hdlq84X38.433.4−40.49.3rs13483831MF, MKK, Add
Non-HDL cholesterolNhdlq13167.756.7−78.73.2rs6185344MF, FKK, Rec
Nhdlq14332.429.2−35.24.5rs6198234MFHet, UDom
542.823.8−55.82.3rs3667334FKK, Dom
764.050.0−79.02.3rs13479455FI, Add
1441.919.9−54.92.2rs6156908FKK, Add
X38.318.4−61.43.3rs13483831MF, FKK, Add
  • QTL, quantitative trait loci; CI, confidence interval; LOD, logarithm of the odds ratio; HDL, high-density lipoprotein.

  • a QTL were named if they were significant or if they were suggestive but confirmed QTL reported previously.

  • b Significant LOD scores were determined by 1000 permutations for the autosomes and 16,803 permutations for Chr X and are indicated in bold.

  • c Apoa2 is the likely causative gene.