Table 1 Genetic interactions between slp1Δ or emp65Δ and SPB mutants
SPB MutantSPB Defectslp1Δ::KANMXemp65Δ::KANMX
mps3Δ75-150None
mps3-Y502HHB assemblySLSS
mps3-A540DHB assemblySSSL
mps3-F592SHB assembly, SPB insertionSLSL
mps3-1HB assembly
cdc31-2HB assembly
kar1Δ17HB assembly
sfi1-3HB assembly
sfi1-7HB elongation
spc42-11satellite formation
spc29-3satellite formation
spc110-220nMT assembly
tub1-4nMT and cMT assembly
bbp1-1SPB insertion
ndc1-39SPB insertion
mps2-1SPB insertion
mps1-8satellite formation
  • All genetic interactions were scored on YPD at 23°. SL, synthetic lethal; SS, synthetic sick; -, no genetic interaction.