Table 4 QTL SIMULATION STUDY
Sample SizeWithin 10 Mb*False PositivesAvg. Proportion Recessive *Min. Proportion Recessive *Avg. p-value (–log10) *Avg. Distance From Known Locus (bp) *
2039%36%58.7%40.00%63.478,994,347
40100%0%56.1%37.50%10.721,623,113
60100%0%57.83%46.67%15.12748,586
80100%0%57.89%51.25%19.38678,954
100100%0%57.77%53.00%23.88675,179
Sample SizeWithin 10 Mb*False PositivesAvg. Proportion Recessive *Min. Proportion Recessive *Avg. p-value (–log10) *Avg. Distance From Known Locus (bp) *
2037%25%27.8%15.00%6.575,703,808
4085%6%24.9%12.50%7.802,790,210
60100%0%24.7%16.67%10.302,269,732
80100%0%25.2%17.50%12.492,111,612
100100%0%25.3%20.00%15.152,177,236
  • * Only if significant with a Bonferroni correction at –log10(p) ≥ 5.2074 and in the right location (within 10 Mb)