Table 4 Reversion spectra of the (CTGCC)6 repeat
(CTGCC)6
Relevant Genotype(CTGCC)4 −10 bp(CTGCC)7 +5 bp(CTGCC)10 +20 bp
Wild type1150
msh2190
msh30100
msh6271
mlh1a6100
exo1280
  • Repeat tract changes were determined from random independent revertants.

  • a Distribution of deletions and insertions in mlh1 background significantly different to wild type (χ2 = 4.57; p = 0.033). Reversion spectra of all other mutants were not significantly different to wild type.