Table 5 Reversion rates of hepta-nucleotide repeats
Hepta-Nucleotide Repeat
(ATCGTCC)5ΔT(ATCGTCC)5
Relevant GenotypeRateaFold Increasebp-ValuecRateFold Increasep-Value
Wild type7.2 ± 3.2 × 10−617.5 ± 2.9 × 10−61
msh27.3 ± 1.8 × 10−610.996.8 ± 0.9 × 10−60.90.7
msh31.4 ± 0.7 × 10−51.90.132.1 ± 0.6 × 10−52.80.0008
msh65.2 ± 3.2 × 10−60.70.41.0 ± 0.4 × 10−51.30.34
mlh16.2 ± 2.3 × 10−60.90.664.7 ± 0.9 × 10−60.60.15
exo11.2 ± 0.4 × 10−51.70.122.2 ± 0.9 × 10−52.90.0066
  • a Numbers are mean values with SDs.

  • b Relative to wild type.

  • c p-values were calculated by a two-tailed Student’s t-test in comparison to wild type.