Table 2 Reversion rates of GACC tetra-nucleotide repeats
Tetra-Nucleotide Repeat
(GACC)8(GACC)7ΔT
Relevant GenotypeRateaFold Increasebp-ValuecRateFold Increasep-Value
Wild type1.2 ± 0.6 × 10−512.1 ± 2.0 × 10−51
msh25.3 ± 2.7 × 10−4440.0024.6 ± 3.2 × 10−4220.009
msh36.3 ± 3.6 × 10−60.50.155.2 ± 1.3 × 10−60.20.15
msh64.7 ± 2.8 × 10−4390.0064.6 ± 1.8 × 10−4220.0001
mlh15.3 ± 2.5 × 10−4440.0023.5 ± 2.2 × 10−4170.006
exo18.1 ± 0.9 × 10−60.70.337.3 ± 1.8 × 10−60.30.27
  • a Numbers are mean values with SDs.

  • b Relative to wild type.

  • c p-values were calculated by a two-tailed Student’s t-test in comparison to wild type.