Table 3 Reversion rates of the (CTGCC)6 repeat
Relevant GenotypePenta-Nucleotide Repeat (CTGCC)6
RateaFold Increasebp-Valuec
Wild type3.4 ± 0.5 × 10−51
msh25.5 ± 1.9 × 10−51.60.08
msh31.5 ± 0.2 × 10−50.40.0005
msh64.9 ± 2.7 × 10−51.40.32
mlh14.3 ± 0.7 × 10−51.30.09
exo13.5 ± 1.2 × 10−510.95
  • a Numbers are mean values with SDs.

  • b Relative to wild type.

  • c p-values were calculated by a two-tailed Student’s t-test in comparison to wild type.