Table 7 Reversion rates of (ATCGTCC)5 repeats in msh3, exo1, and rad mutants
(ATCGTCC)5
p-Valuesc
Relevant GenotypeRateaFold Increasebvs. WTvs.msh3vs.exo1vs.rad
Wild type7.5 ± 2.9 × 10−61
msh32.1 ± 0.6 × 10−52.80.0008
exo12.2 ± 0.9 × 10−52.90.0066
msh3 exo15.7 ± 0.5 × 10−60.80.00490.032
rad21.5 ± 0.7 × 10−520.043
rad501.4 ± 0.4 × 10−51.90.016
rad511.7 ± 0.6 × 10−52.30.0087
msh3 rad22.1 ± 0.5 × 10−52.80.980.24
msh3 rad502.6 ± 0.7 × 10−53.50.260.033
msh3 rad512.2 ± 2.1 × 10−60.30.00180.01
exo1 rad502.7 ± 0.8 × 10−53.60.240.025
exo1 rad517.0 ± 3.1 × 10−60.90.0110.013
  • a Numbers are mean values with SDs. Values from wild type, msh3, and exo1 derived from Table 5 and are shown for comparison.

  • b Relative to wild type.

  • c p-values were calculated by a two-tailed Student’s t-test in comparison to the indicated strains. WT, wild type; rad, rad2FEN1, rad50, or rad51 single mutants.