Table 4 The least-squares regressions of frequencies of individuals bearing a specified network or SNP vs. latitude for the populations indicated in Table 1 from the frequency and sample size data given in Table 4
Network/SNPGenesInterceptSlopeQuadratic TermR2
65_1TYRP1, TYR, VDR0.752–0.0074**n.s.0.70
70_1TYRP10.977–0.0082***n.s.0.76
rs1042602TYR0.8900.0065*n.s.0.56
70_5VDR0.848n.s.–0.0002*0.53
70_5–AfVDR0.920–0.0027**n.s.0.68
65_2VDR, MC1R, SLC24A5, SLC45A2−0.0660.0200***n.s.0.84
70_4VDR0.6080.0104*–0.0007*0.73
70_4–AfVDR0.858n.s.n.s.0.15
rs4073729VDR0.858n.s.–0.0002*0.50
rs4073729–AfVDR0.942–0.0023*n.s.0.61
rs2228478MC1R0.7410.0066**–0.0005**0.85
rs2228478–AfMC1R0.877n.s.n.s.0.21
rs3212369MC1R0.5750.0063**n.s.0.59
rs1426654SLC24A50.5790.0130**–0.0007*0.80
rs1426654–AfSLC24A50.810n.s.n.s.0.24
rs16891982SLC45A2−0.1360.0209***n.s.0.86
65_3MC1R0.3630.0125***–0.0005**0.91
65_3–AfMC1R0.5110.0064**n.s.0.69
65_4VDR0.983n.s.n.s.0.29
65_5VDR0.462n.s.n.s.0.36
65_6VDR0.671n.s.n.s.0.00
65_7MC1R0.728n.s.n.s.0.06
  • * Significant with P ≤ 0.05, ** significant with P ≤ 0.01, *** significant with P ≤ 0.001. SNP, single nucleotide polymorphism; n.s., not significant; –Af, the sub-Saharan African populations were excluded from the regression analysis.