Table 2 poml-1 suppression of mec-4(d) requires mec-10 and mec-19
GeneAlleleMutationD/R% ALM% PLM
mec-10u883TGG > TGA, 95W > StopSemi-D00
u884CAG > TAG, 147Q > StopSemi-D04
u885TGG > TGA, 618W > StopR02
u886TGC > TAC, 170C > YR03
u887TCC > TTC, 471S > FR212
u888CGC > TGC, 507R > CR16
u889TGC > TAC, 557C > YR213
u890GTG > ATG, 573V > MR517
u891G > A splicing junction, exon 2 - intron 2R15
u892G > A splicing junction, exon 6 - intron 6R211
u893A > T the 3rd nucleotide, intron 6R28
u894G > A splicing junction, exon 9 - intron 9Semi-D22
u895G > A splicing junction, exon 14 - intron 14Semi-D14
u896G > A, the 5th nucleotide, intron 16R21
u897DeletionaSemi-D618
mec-19u898Deletion of the first exonR12
mec-3u899T > A, the 5th last nucleotide, intron 2 of isoform aR01
  • D, dominant; R, recessive.

  • a DNA from u897 animals could not be amplified using primers that were 120 bp upstream of the start ATG and 80 bp downstream of the stop codon. n = 50 animals.