Table 3 Snl1 mutants obtained from random mutagenesis that is unable to cure [URE3]
Snl1 MutationBAG-1 ResidueHsc70 Interaction
S89NQ187Not known
D122ND222R262
E147KK243Not known
D156ND252R258
R141MR237Y294, E283
L114FF214Not known
L114VF214Not known
A150PA246Not known
  • Corresponding wild-type residues in BAG-1 protein and its Hsc70-interacting residues also are shown.